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Sugar daddy sites started popping up on the Internet about a decade ago, but the top three sites in the Bay Area have reported a dramatic acceleration over the last three or four years of Tech Boom 2.0.

"I believe it was while climbing a rope when I was ...

more Gwyneth Paltrow is surprisingly open to new experiences when it coms to sex.

“I'm down with all of them," she told UK chat show host Amanda De Cadenet when asked about favorite sexual positions in 2012.

Click through the gallery to see other sex confessions — from celebrities. Her claim that her hit "Supernatural" was written about a sexual experience with..for it...a ghost (! If I were in a really raunchy frame of mind and thinking ...

If you're going to make a celebrity sex confession at least do it to the appropriate publication. It was like napalm, sexual napalm." You said quite enough, John. During an 2010 interview with Jimmy Kimmel, the singer went on to allege the ghost got stuck in her... more Jessica Simpson, the victim of John Mayer's sexual confession, made a reveal of her own to Ryan Seacrest in 2012. " Maybe that's why Simpson rushed immediately into a second pregnancy?

John Mayer did just that in a 2010 interview with Playboy when he spoke candidly about ex-girlfriend Jessica Simpson. less Even though it's fairly normalized these days, sugar daddy culture is still considered fairly scandalous. Her claim that her hit "Supernatural" was written about a sexual experience with..for it...a ghost (! The star, then pregnant with her first child, revealed the following: "I am definitely 'feeling intimate. less Jessica Simpson, the victim of John Mayer's sexual confession, made a reveal of her own to Ryan Seacrest in 2012.

"That girl, for me, is a drug, and drugs aren't good for you if you do lots of them. Click through the gallery to see other sex confessions — from celebrities. The star, then pregnant with her first child, revealed the following: "I am definitely 'feeling ...

more In a 2011 interview with Rolling Stone Magazine, George Clooney revealed that he lost his virginity at age 16 but experienced his first orgasm much earlier.

"I believe it was while climbing a rope when I was 6 or 7 years old," he told the magazine.

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  1. The agent which effects this C-terminal (alpha) amidation recognizes a glycine residue which immediately follows the amino acid to be amidated (R-X-gly, where R is the main body of the protein, X is the residue which is amidated, and "gly" is the glycine residue). 686-688 report an α-amidating enzyme activity to be present in porcine pituitary. When the enzyme has a specific enzymatic activity of about 1 m U/mg protein, maximum α-amidation occurs with a concentration of 4.7 u M cupric ions.

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